Experimentally-driven protein structure modeling
نویسندگان
چکیده
منابع مشابه
Comparing and Modeling Protein Structure
Proteins are remarkably versatile macromolecules involved in essentially all biological processes. The detailed three-dimensional structure of a protein encodes its function. A fundamental computational challenge in the study of proteins is the comparison and modeling of protein structure. Structural similarities of proteins can hint at distant evolutionary relationships that are impossible to ...
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We present an efficient method of combining wide angle neutron scattering data with detailed atomistic models, allowing us to perform a quantitative and qualitative mapping of the organisation of the chain conformation in both glass and liquid phases. The structural refinement method presented in this work is based on the exploitation of the intrachain features of the diffraction pattern and it...
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ژورنال
عنوان ژورنال: Journal of Proteomics
سال: 2020
ISSN: 1874-3919
DOI: 10.1016/j.jprot.2020.103777